libRoadrunner

A high performance and portable simulation engine for systems and synthetic biology.

Three extensive APIs designed specially for modelers. These links point to documentation local to the system. For up to date documentation please visit: http://libroadrunner.org

1. C++ API
2. C API
3. Python bindings
4. C Plugin API
5. C++ Plugin API

libRoadRunner 1.0 supports the following features:

• Time Dependent Simulation (with optional conservation law reduction) using CVODE from the sundials suite.
• Steady State evaluation using NLEQ2
• Supports SBML Level 2 to 3 but currently excludes algebraic rules and delay differential equations
• Uses latest libSBML distribution
• Defaults to LLVM code generation on the backend, resulting is very fast simulation times
• Optional generation of model C code and linking at run-time
• Add plugins, distribution comes with Levenberg-Marquardt optimizer plugin
• Supports Metabolic Control Analysis
• Supports Frequency Domain Analysis
• Additional Plugin API (C and C++)
• APIs support fast access to model quantities
• Access to other items such as:

1. Eigenvalues and Eigenvectors
2. Jacobian, full and reduced
3. Structural Matrices of the stoichiometry matrix

Availability

RoadRunner is licensed for free as an open source (Apache License, Version 2.0)  programmatic library for use in other applications without restriction and as a�standalone command line driven application.

On Windows, OS X, and Linux binary files can be downloaded from http://sourceforge.net/projects/libroadrunner/files and installed ready for use.

Acknowledgements

This work is funded by the generous support of the NIH/NIGMS grant: GM081070

Licence

Licensed under the Apache License, Version 2.0 (the “License”); you may not use this file except in compliance with the License. You may obtain a copy of the License at

http://www.apache.org/licenses/LICENSE-2.0

Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an “AS IS” BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the License for the specific language governing permissions and limitations under the License.

In plain English this means:

You CAN freely download and use this software, in whole or in part, for personal or commercial purposes without restriction.

You CAN use the software in packages or distributions that you create.

You SHOULD include a copy of the license in any redistribution you may make;

You are NOT required include the source of software, or any modifications you may have made to it, in any redistribution you assemble.

YOU CANNOT: redistribute any piece of this software without proper attribution

 

 

libroadrunner logo

The libroadrunner logo is an adaptation of the image originally posted to Flickr by El Brujo+ at http://flickr.com/photos/11039104@N08/2954808342. It was reviewed on 9 August 2009 by the FlickreviewR robot and was confirmed to be licensed under the terms of the cc-by-sa-2.0.